| Phenotype: | macrophage interleukin-4-mediated signaling pathway increased efficacy, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | macrophage |
|---|---|
| Synonyms: | histiocyte |
| Definition: | A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. |
| Ontology: | Anatomy Ontology [ZFA:0009141] |
| Name: | interleukin-4-mediated signaling pathway |
|---|---|
| Synonyms: | IL-4-mediated signaling pathway, interleukin-4-mediated signalling pathway |
| Definition: | The series of molecular signals initiated by interleukin-4 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| Ontology: | GO: Biological Process [GO:0035771] QuickGO AmiGO |
| Name: | increased efficacy |
|---|---|
| Synonyms: | |
| Definition: | A increase in the ability of a process to produce its output. |
| Ontology: | Phenotypic Quality Ontology [PATO:0015004] |