| Phenotype: | spleen macrophage aggregated, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | spleen |
|---|---|
| Synonyms: | |
| Definition: | Organ that filters the blood removing defective blood cells. The spleen is a dark red organ, located in the peritoneal cavity, adjacent to one of the liver lobes. The spleen consists of red pulp composed of erythrocytes and thrombocytes and white pulp, composed of macrophages, reticular cells and reticulin fibers. |
| Ontology: | Anatomy Ontology [ZFA:0000436] |
| Name: | macrophage |
|---|---|
| Synonyms: | histiocyte |
| Definition: | A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. |
| Ontology: | Anatomy Ontology [ZFA:0009141] |
| Name: | aggregated |
|---|---|
| Synonyms: | clumped, clustered |
| Definition: | A spatial pattern inhering in a bearer by virtue of the bearer's being gathered or tending to gather into a mass or whole. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001629] |