| Phenotype: | neural crest cell late endosome decreased amount, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | neural crest cell |
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| Synonyms: | neural crest cells |
| Definition: | A cell of the neural crest. The neural crest is a strip of specialized ectoderm, the neural plate border, which flanks each side of the embryonic neural plate. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesenchymal transition and delamination to form migratory neural crest cells. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells. |
| Ontology: | Anatomy Ontology [ZFA:0009165] |
| Name: | late endosome |
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| Synonyms: | prevacuolar compartment, PVC |
| Definition: | A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. |
| Ontology: | GO: Cellular Component [GO:0005770] QuickGO AmiGO |
| Name: | decreased amount |
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| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |