| Phenotype: | neural crest cell early endosome increased amount, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | neural crest cell |
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| Synonyms: | neural crest cells |
| Definition: | A cell of the neural crest. The neural crest is a strip of specialized ectoderm, the neural plate border, which flanks each side of the embryonic neural plate. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesenchymal transition and delamination to form migratory neural crest cells. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells. |
| Ontology: | Anatomy Ontology [ZFA:0009165] |
| Name: | early endosome |
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| Synonyms: | |
| Definition: | A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. |
| Ontology: | GO: Cellular Component [GO:0005769] QuickGO AmiGO |
| Name: | increased amount |
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| Synonyms: | accessory, increased, increased number, present in greater numbers in organism, supernumerary |
| Definition: | An amount which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000470] |