| Phenotype: | skeletal muscle neuromuscular junction morphology, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | skeletal muscle |
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| Synonyms: | |
| Definition: | Muscle, composed of long cylindrical, multinucleated cells that attaches to the skeleton via tendons. |
| Ontology: | Anatomy Ontology [ZFA:0005277] |
| Name: | neuromuscular junction |
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| Synonyms: | motor endplate, NMJ |
| Definition: | The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. |
| Ontology: | GO: Cellular Component [GO:0031594] QuickGO AmiGO |
| Name: | morphology |
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| Synonyms: | |
| Definition: | A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000051] |