| Phenotype: | pronephric tubule renal principal cell rfx2 expression spatial pattern, abnormal |
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| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | pronephric tubule |
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| Synonyms: | ciliated neck segment |
| Definition: | Bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts. In zebrafish and other teleosts, the pronephric nephron and tubules form after the pronephric duct, connecting to the anterior-most tip of the pronephric ducts. |
| Ontology: | Anatomy Ontology [ZFA:0001558] |
| Name: | renal principal cell |
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| Synonyms: | |
| Definition: | A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the cells apical membrane is regulated by aldosterone and vasopressin. In mammals these cells are located in the renal collecting ducts. |
| Ontology: | Anatomy Ontology [ZFA:0005322] |
EXPRESSED GENE:
| Symbol: | rfx2 | ||||||||||||
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| Name: | regulatory factor X, 2 (influences HLA class II expression) | ||||||||||||
| Previous Names: | cb133 (1), cb7 (1), sb:cb133, sb:cb7, wu:fd20b11, zgc:91808 | ||||||||||||
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| Location: | Chr: 8 Mapping Details/Browsers | ||||||||||||
EXPRESSION QUALITY:
| Name: | spatial pattern |
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| Synonyms: | distribution, pattern |
| Definition: | A spatial quality inhering in a bearer by virtue of the bearer's exhibiting repetition of placement of its parts. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000060] |