Search Ontology:
GO: Biological Process

cGAS/STING signaling pathway

Term ID
GO:0140896
Synonyms
Definition
The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING. (3)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
negatively regulated by
positively regulated by
Phenotype
Phenotype caused by Genes