Search Ontology:
GO: Biological Process

extrinsic apoptotic signaling pathway

Term ID
GO:0097191
Synonyms
  • death receptor-mediated apoptosis
  • extrinsic apoptosis
  • extrinsic apoptotic pathway
  • extrinsic apoptotic signaling pathway in presence of ligand
  • extrinsic apoptotic signalling pathway
Definition
The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. 17340152
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
has parts
is a type of
has subtype
inverse has_part
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes