Search Ontology:
GO: Cellular Component

NF-kappaB complex

Term ID
GO:0071159
Synonyms
Definition
A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression. 0849327946
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
has subtype
Phenotype
Phenotype caused by Genes