Search Ontology:
GO: Biological Process

calcitriol biosynthetic process from calciol

Term ID
GO:0036378
Synonyms
  • 1alpha,25(OH)2D3 biosynthesis
  • 1alpha,25-dihydroxycholecalciferol biosynthesis
  • 1alpha,25-dihydroxyvitamin D3 biosynthesis
  • calcitriol biosynthesis from calciol
  • vitamin D3 activation
Definition
Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol. (2)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
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Phenotype
Phenotype caused by Genes