Search Ontology:
GO: Cellular Component

TSC1-TSC2 complex

Term ID
GO:0033596
Synonyms
  • tuberin-hamartin complex
  • tuberous sclerosis complex
Definition
A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway. (3)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is part of
is a type of
Phenotype
Phenotype caused by Genes