Search Ontology:
GO: Biological Process

granzyme-mediated apoptotic signaling pathway

Term ID
GO:0008626
Synonyms
  • apoptotic signaling pathway in response to granzyme
  • induction of apoptosis by granzyme
Definition
The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. 17158907
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes