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ChEBI

8-acetoxy-4,10-dihydroxy-2,11(13)-guaiadiene-12,6-olide

Term ID
CHEBI:65363
Synonyms
  • (3aR,4S,6R,6aR,9R,9aS,9bS)-6,9-dihydroxy-6,9-dimethyl-3-methylidene-2-oxo-2,3,3a,4,5,6,6a,9,9a,9b-decahydroazuleno[4,5-b]furan-4-yl acetate
Definition
A sesquiterpene lactone and an organic heterotricyclic compound that is 2,3,3a,4,5,6,6a,9,9a,9b-decahydroazuleno[4,5-b]furan substituted by an acetoxy group at position 4, hydroxy groups at positions 6 and 9, methyl groups at positions 6 and 9, a methylidene group at position 3 and an oxo group at position 2. It is a guaianolide isolated from Chrysanthemum boreale and has been shown to exhibit cytotoxic activity against human cancer cell lines.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from 8-acetoxy-4,10-dihydroxy-2,11(13)-guaiadiene-12,6-olide
Phenotype where environments contain 8-acetoxy-4,10-dihydroxy-2,11(13)-guaiadiene-12,6-olide
Phenotype modified by environments containing 8-acetoxy-4,10-dihydroxy-2,11(13)-guaiadiene-12,6-olide
Human Disease / Model Data