Search Ontology:
ChEBI
vandetanib
- Term ID
- CHEBI:49960
- Synonyms
-
- 4-BROMO-2-FLUORO-N-[(4E)-6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]QUINAZOLIN-4(1H)-YLIDENE]ANILINE
- N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
- vandetanib
- Zactima
- ZD 6474
- ZD6474
- Definition
- A quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
- References
-
- CAS:443913-73-3
- DrugBank:DB08764
- Drug_Central:4178
- KEGG:D06407
- LINCS:LSM-1199
- PDBeChem:ZD6
- PMID:12684431
- PMID:14760102
- PMID:15305185
- PMID:15367698
- PMID:15596048
- PMID:15604279
- PMID:15623642
- PMID:15623658
- PMID:15928657
- PMID:16140331
- PMID:16179094
- PMID:16299247
- PMID:16361567
- PMID:16377413
- PMID:16688779
- PMID:16783964
- PMID:16843002
- PMID:17136225
- PMID:17393165
- PMID:17409986
- PMID:17631646
- PMID:17878479
- PMID:17912240
- PMID:18228115
- PMID:18698025
- PMID:18936474
- PMID:19002384
- PMID:19088171
- PMID:19211364
- PMID:19220256
- PMID:19332730
- PMID:19349511
- PMID:19394692
- PMID:19512898
- PMID:19622715
- PMID:19687425
- PMID:19881951
- PMID:19883226
- PMID:19946413
- PMID:20371720
- PMID:21046425
- PMID:21353546
- PMID:21718364
- PMID:22075979
- PMID:22158569
- PMID:22169262
- PMID:22184381
- PMID:22245891
- PMID:22307735
- PMID:22343387
- PMID:22346266
- PMID:22370318
- PMID:22500115
- PMID:22505191
- PMID:22608542
- PMID:22611027
- PMID:22633931
- PMID:22665903
- PMID:22667325
- PMID:22701615
- PMID:22781612
- PMID:22830347
- PMID:22898678
- PMID:22938056
- Patent:US2006135486
- Patent:US2008032989
- Patent:US2008199480
- Patent:WO2005115145
- Patent:WO2006005915
- Patent:WO2007036713
- Patent:WO2008001101
- Patent:WO2008007113
- Patent:WO2009024825
- Patent:WO2012055015
- Reaxys:9161676
- Wikipedia:Vandetanib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
- inverse has_functional_parent
-
Phenotype
Phenotype resulting from vandetanib
Phenotype where environments contain vandetanib
Phenotype modified by environments containing vandetanib
Human Disease / Model Data