Search Ontology:
ChEBI

eltanexor

Term ID
CHEBI:229762
Synonyms
  • (2E)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)prop-2-enamide
  • (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1,2,4-triazol-1-yl)-2-pyrimidin-5-ylprop-2-enamide
  • ATG-016
  • eltanexor
  • eltanexorum
  • KPT 8602
  • KPT-8602
  • KPT8602
  • ONO-7706
Definition
A member of the class of triazoles that is 1H-1,2,4-triazole substituted by (1E)-3-amino-3-oxo-2-(pyrimidin-5-yl)prop-1-en-1-yl and 3,5-bis(trifluoromethyl)phenyl groups at positions 1 and 3, respectively. It is a second-generation exportin 1 inhibitor that is currently in phase II clinical trial for the treatment of patients with higher relapsed/refractory myelodysplastic neoplasms.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from eltanexor
Phenotype where environments contain eltanexor
Phenotype modified by environments containing eltanexor
Human Disease / Model Data