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ChEBI

N-glycolylneuraminyllactosylceramide

Term ID
CHEBI:144806
Synonyms
  • (2S,3R,4E)-3-hydroxy-2-(octadecanoylamino)octadec-4-en-1-yl 3,5-dideoxy-5-(2-hydroxyacetamido)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside
  • (2S,3R,4E)-3-hydroxy-2-(stearoylamino)octadec-4-en-1-yl 3,5-dideoxy-5-(glycoloylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside
  • (5alpha,17alpha)-N-deacetyl-N-(hydroxyacetyl)-ganglioside GM3
  • 1-O-(O-(N-(hydroxyacetyl)-alpha-neuraminosyl)-(2-3)-O-beta-D-galactopyranosyl-(1-4)-beta-D-glucopyranosyl)-ceramide
  • GM3-Neugc
  • HD3 ganglioside
  • N-glycoloyl-GM3
  • N-glycolyl-neuraminyl-lactosyl-ceramide
  • Neugc(alpha2-3)gal(beta1-4)glc(beta1-1)cer
  • Neugc-GM3
Definition
A sialotriaosylceramide in which the triaosyl group is 3,5-dideoxy-5-(2-hydroxyacetamido)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl attached to the primary hydroxy function of ceramide. A tumour antigen found in solid tumors such as breast carcinoma, nonsmall cell lung cancer, and melanoma, but not usually detected in normal human cells.
References
Ontology
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Relationships
is a type of
has_role
Phenotype
Phenotype resulting from N-glycolylneuraminyllactosylceramide
Phenotype where environments contain N-glycolylneuraminyllactosylceramide
Phenotype modified by environments containing N-glycolylneuraminyllactosylceramide
Human Disease / Model Data