Search Ontology:
ChEBI

golgicide A

Term ID
CHEBI:139037
Synonyms
  • 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
  • GCA
Definition
A diastereoisomeric mixture comprising racemic cis- and racemic trans-goglioside A in a 10:1 ratio. It is a potent and rapidly reversible GBF1 (Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1) inhibitor. The (3aS,4R,9bR) isomer is the most active (see Bioorg. Med. Chem. Lett., 2012, 22, 5177-5181).
References
  • CAS:1005036-73-6
  • Pubchem:25113626
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from golgicide A
Phenotype where environments contain golgicide A
Phenotype modified by environments containing golgicide A
Human Disease / Model Data