Search Ontology:
ChEBI

CFTRinh-172

Term ID
CHEBI:131686
Synonyms
  • (inh)-172
  • 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone
  • 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid
  • 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone
  • C2992_SIGMA
  • CFTR(inh)-172
  • Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172
  • cystic fibrosis transmembrane regulator inhibitor 172
Definition
A thiazolidinone that is 2-thioxo-4-thiazolidinone which is substituted at position 3 by a (m--trifluoromethyl)phenyl group and at position 5 by a p-carboxybenzylidene group. It is an inhibitor of cystic fibrosis transmembrane conductance regulator, a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from CFTRinh-172
Phenotype where environments contain CFTRinh-172
Phenotype modified by environments containing CFTRinh-172
Human Disease / Model Data