Term Name: | hycanthone |
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Synonyms: | 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one, 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one, 1-(2-diethylaminoethylamino)-4-(hydroxymethyl)thioxanthen-9-one, 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one, hicantona, Hycanthon, hycanthone, hycanthonum, Lucanthone metabolite |
Definition: | A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel. |
Ontology: | ChEBI [CHEBI:52768] ( EBI ) |