Term Name: | zileuton |
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Synonyms: | (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea, 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea, Leutrol, N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea, N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea, zileuton, zileutonum, Zyflo |
Definition: | A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma. |
Ontology: | ChEBI [CHEBI:10112] ( EBI ) |