Person
Lane, Mary Ellen
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Biography and Research Interest
My research interests include the specification of axial pattern in the developing central nervous system. I am using a combination of genetics molecular biology and experimental embryology to dissect the earliest events involved in induction and patterning of the CNS, with a particular focus on posterior neuroectoderm.
Non-Zebrafish Publications
Original ReportsLane, M.E., and Kalderon, D. 1993. Genetic investigation of cAMP-dependent protein kinase function in Drosophila development. Genes and Dev. 7, 1229-1243.
Lane, M.E., and Kalderon, D. 1994. RNA localization along the anteroposterior axis of the Drosophila oocyte requires PKA-mediated signal transduction to direct normal microtubule organization. Genes and Dev. 8, 2986-2995.
Lane, M.E., and Kalderon, D. 1995. Localization and function of protein kinase A during Drosophila oogenesis. Mech. of Dev. 49, 191-200.
Li, W., Ohlmeyer, J.T., Lane, M.E., and Kalderon, D. 1995. Function of protein kinase A in hedgehog signal transduction and Drosophila imiginal disc development. Cell 80, 553-562.
Lane, M.E., Sauer, K., Wallace, K., Jan, Y.N., Lehner, C.F., and Vaessin, H. 1996. DACAPO, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell 87, 1225-1235.
Thomas, B.J., Zavitz, K.H., Dong, X., Lane, M.E., Weigmann, K., Finley, R.L. Jr., Brent, R., Lehner, C.F. and Zipursky, S.L. 1997. roughex down-regulates G2 cyclins in G1. Genes and Dev. 11, 1289-1298.
Review
Lehner, C.F., and Lane, M.E. Cell cycle regulators in Drosophila: Downstream and part of developmental decisions. J. Cell Sci. 110, 523-528.