Biography and Research Interest

Wesleyan University (B.A.)
Johns Hopkins Medical School (Ph.D.)
Massachusetts Institute of Technology (postdoc)

Publications

Non-Zebrafish Publications

Wu X, Li Y, Crise B, Burgess SM. Transcription start regions in the human genome are favored targets for MLV integration Science. 2003 Jun 13;300(5626):1749-51

LaFave MC, Varshney GK, and Burgess SM (2015). GeIST: a pipeline for mapping integrated DNA elements. Bioinformatics pii: btv350. [Epub ahead of print] doi: 10.1093/bioinformatics/btv350

Chandler RJ, LaFave MC, Varshney GK, Trivedi NS, Carrillo-Carrasco N, Senac JS, Wu W, Hoffmann V, Elkahloun AG, Burgess SM, Venditti CP (2015). Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy. J Clin Invest 125:870-80

Walia JS, Altaleb N, Bello A, Kruck C, LaFave MC, Varshney GK, Burgess SM, Chowdhury B, Hurlbut D, Hemming R, Kobinger GP, Triggs-Raine B (2015). Long-term correction of sandhoff disease following intravenous delivery of rAAV9 to mouse neonates. Mol Ther 23:414-22

Renaud G, LaFave MC, Liang J, Wolfsberg TG, Burgess SM (2014). trieFinder: an efficient program for annotating Digital Gene Expression (DGE) tags. BMC Bioinformatics 15:329

LaFave MC, Varshney GK, Gildea DE, Wolfsberg TG, Baxevanis AD, Burgess SM (2014). MLV integration site selection is driven by strong enhancers and active promoters. Nucleic Acids Res 42:4257-69 PMC3985626

Chen L, Stuart L, Ohsumi TK, Burgess S, Varshney GK, Dastur A, Borowsky M, Benes C, Lacy-Hulbert A, Schmidt EV (2013). Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics. BMC Cancer 13:93 PMC3598783

Milla LA, Cortes CR, Hodar C, Onate MG, Cambiazo V, Burgess SM, Palma V (2012). Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development. BMC Dev Biol 12:16 PMC3285088

Zeng J, Yan J, Wang T, Mosbrook-Davis D, Dolan KT, Christensen R, Stormo GD, Haussler D, Lathrop RH, Brachmann RK, Burgess SM (2008). Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins. Nucleic Acids Res 36: e8. PMC2248728

Wang T, Zeng J, Lowe CB, Yang M, Burgess SM, Brachmann RK, Haussler D (2007). Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53. Proc Natl Acad Sci USA 104: 18613-8. PMC2141825

Wu X, Luke BT, and Burgess SM (2006). Redefining the common insertion site. Virology 344: 292-5.

18. Yant SR, Wu X, Huang Y, Garrison B, Burgess SM, and Kay MA (2005). High-resolution genome-wide mapping of transposons integration in mammals. Mol Cell Biol 25: 2085-94

Wu X, Li Y, Crise B, Burgess SM, and Munroe D (2005). Weak palindromic consensus sequence is a common feature found at integration target sites of many retroviruses. J Virol 79: 5211-4

Nakai H, Wu X, Fuess S, Storm T, Munroe D, Montini E, Burgess SM, Grompe M, and Kay MA (2005). A large-scale molecular characterization of adeno-associated virus vector integration in mouse liver. J Virol 79: 1749-51

Youngman MJ, Hobbs AE, Burgess SM, Srinivasan M, and Jensen RE (2004). Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol 164: 677-88