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Fig. 8
Injection of WT human RERE mRNA results in cyclopia. Injecting increasing concentration of human RERE mRNA results in dose-dependent increase in cyclopia phenotype (A–C). Whole mount in situ hybridization staining of 24 hpf WT and rerea mutant zebrafish embryos with patched2 (D, F) and shha (E, G) probes. Representative images with numbers of embryos showing this pattern are given in each panel.
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