Figure 4

Thyroid hormone deficiency slows down caudal fin regeneration but only during the late phases of regeneration

(A–C) The impact of duox^sa9892, but not tshr^wpr23e1, on the rate of regeneration is significant during 0-1wpa. By 2wpa (B) the effect of tshr^wpr23e1 becomes significant, and this effect continues into 2-3wpa (C).

(D) An overall view across 0-3wpa indicates duox^sa9892 and tshr^wpr23e1 animals are significantly slower than WTs during regeneration. Asterisks denote statistically significant differences (Bonferroni’s multiple comparisons test, ∗p < 0.5, ∗∗p < 0.01, ∗∗∗∗p < 0.0001). WT (n = 25); duox^sa9892 (n = 12); tshr^wpr23e1 (n = 3).

See also Figure S9.