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FIGURE 4
Fibroblast growth factor 21 accelerates liver cell regeneration after injury. Samples were collected at 0, 24, and 48 hpa to assess the production of new cells in the damaged liver. PCNA assay performed to assess the level of the formation of new cells in the damaged liver. Liver cells (green fluorescent Denra-NTR), stromal cells (blue fluorescent DAPI), and PCNA positive cells (red fluorescent). DMSO group: without Mtz treatment, DMSO was applied. Mtz group: after Mtz treatment, grow naturally. Mtz+FGF21 group: after Mtz treatment, treated with FGF21 standard protein (n = 40 per group, repeat 3 times for each test). Scale bar = 100 μm.