ZFIN Image: Swartz et al., 2021, Fig 7

Image

Figure Caption

Fig 7 Gata3 functions downstream of Bmp in palate development.

(A-C) Flat mounts of 4 dpf neurocrania anterior to the left. (A) Wild type phenotype of the hsp:DN-BmpR1a with no heat shock. (B) Severely affected trabeculae typical of the hsp:DN-BmpR1a when heat shocked at 24 hpf. (C) A typical rescue of the hsp:DN-BmpR1a;hsp:GATA3-EGFP heat shock phenotype at 24 hpf. (D) Graph depicting quantification of heat shock phenotype scores at three different heat shock time points. Trabeculae phenotype is rescued significantly by hsp:GATA3-EGFP at 24 and 26 hpf. Phenotypes are also rescued at 28 hpf, but to a lesser degree as the overall phenotype is not as severe. A two way ANOVA was performed with Holm-Sidak’s multiple comparisons test. At all heat shock timepoints the hsp:DN-BmpR1a controls had significantly worse phenotype when compared to the hsp:DN-BmpR1a;hsp:GATA3-EGFP double heat shock.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.