ZFIN Image: Pei et al., 2020, Fig. 1

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Figure Caption

Fig. 1 Hair cell regeneration analysis for mutations in each gene of the SMN complex.

Hair cell regeneration is impaired by homozygous mutations of gemin3^hg105a, smn1^hg104b, and gemin5^hg107c, but not in gemin2^hg108d, gemin4^hg109e, gemin6^hg110f, gemin7^hg111g, gemin8^hg112h, or strap^hg113i. Red line separates the mutations impacting regeneration from those that have no effect on regeneration. wt wild-type, het heterozygotes, hom homozygotes. Error bars in the graphs represent mean ± s.e.m. The difference between wild-type and homozygote is labeled. ns, P > 0.05; ***P < 0.001; ****P < 0.0001. Approximately 40 embryos were used for each of the regeneration analyses and then genotyped to study the genotype–phenotype correlation.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ NPJ Regen Med