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Fig. S8
ace/fgf8 mutants result in the broken-up DFC phenotype. (A-C) Upper panels indicate sox32 expression in wild type (+/+; A), ace heterozygote (ace/+; B), ace homozygote (ace/ace; C) at 70% epiboly. Scale bar: 200 μm. Lower panels show sequences around the ace mutation. Arrows indicate the position of the ace mutation. Substitution from G to A occurs in the ace allele. (D) Percentages of normal or broken-up DFCs were scored using the sox32 expression pattern in wild type (n = 17), ace heterozygote (n = 36) or ace homozygote (n = 14).
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