Gene

mrap2b

ID
ZDB-GENE-100729-5
Name
melanocortin 2 receptor accessory protein 2b
Symbol
mrap2b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Exhibits receptor regulator activity and type 4 melanocortin receptor binding activity. Involved in several processes, including energy homeostasis; energy reserve metabolic process; and positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway. Localizes to Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in obesity. Is expressed in several structures, including adipose tissue; heart; liver; nervous system; and pleuroperitoneal region. Orthologous to human MRAP2 (melanocortin 2 receptor accessory protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mrap2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{?Obesity, susceptibility to, BMIQ18} 615457
Associated With mrap2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR028111 Melanocortin-2 receptor accessory protein family
Domain Details Per Protein
Protein Length Melanocortin-2 receptor accessory protein family
UniProtKB:P0DM64 199
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations