Gene
dlg2
- ID
- ZDB-GENE-050221-3
- Name
- discs, large homolog 2 (Drosophila)
- Symbol
- dlg2 Nomenclature History
- Previous Names
-
- PSD-93 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; negative regulation of phosphatase activity; and receptor clustering. Predicted to colocalize with ionotropic glutamate receptor complex. Is expressed in nervous system and neural tube. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020590 | Guanylate kinase, conserved site |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR004172 | L27 domain |
| Domain | IPR008144 | Guanylate kinase-like domain |
| Domain | IPR008145 | Guanylate kinase/L-type calcium channel beta subunit |
| Domain | IPR015143 | L27-1 |
| Domain | IPR019583 | Disks large homolog 1-4, PDZ-associated domain |
| Domain | IPR019590 | Disks large homologue 1, N-terminal PEST domain |
| Domain | IPR035759 | Disks Large homologue 2, SH3 domain |
| Family | IPR016313 | Disks large 1-like |
| Family | IPR050614 | Synaptic Scaffolding LAP/MAGUK Families |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036892 | L27 domain superfamily |
Domain Details Per Protein
| Protein | Length | Disks large 1-like | Disks large homolog 1-4, PDZ-associated domain | Disks large homologue 1, N-terminal PEST domain | Disks Large homologue 2, SH3 domain | Guanylate kinase, conserved site | Guanylate kinase-like domain | Guanylate kinase/L-type calcium channel beta subunit | L27-1 | L27 domain | L27 domain superfamily | PDZ domain | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase | SH3 domain | SH3-like domain superfamily | Synaptic Scaffolding LAP/MAGUK Families |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B3D7
|
858 | ||||||||||||||||
|
UniProtKB:A0A8M3B6B1
|
1044 | ||||||||||||||||
|
UniProtKB:A0A8M3BD50
|
959 | ||||||||||||||||
|
UniProtKB:A0A8M3BD41
|
987 | ||||||||||||||||
|
UniProtKB:A0A8M3AWU6
|
1068 | ||||||||||||||||
|
UniProtKB:A0A8M3AWX6
|
1031 | ||||||||||||||||
|
UniProtKB:A0A8M3B6A6
|
1065 | ||||||||||||||||
|
UniProtKB:A0A8M3B6B8
|
972 | ||||||||||||||||
|
UniProtKB:A0A8M3B6B4
|
1010 | ||||||||||||||||
|
UniProtKB:A0A8M3BD31
|
1075 | ||||||||||||||||
|
UniProtKB:A0A8M3AWV4
|
1022 | ||||||||||||||||
|
UniProtKB:A0A8M9QC28
|
860 | ||||||||||||||||
|
UniProtKB:A0A8M3AWW9
|
1075 | ||||||||||||||||
|
UniProtKB:A0A8M3B3D0
|
1002 | ||||||||||||||||
|
UniProtKB:A0A8M3AWX1
|
1060 | ||||||||||||||||
|
UniProtKB:A0A8M3AWW5
|
931 | ||||||||||||||||
|
UniProtKB:A0A8M3BD47
|
961 | ||||||||||||||||
|
UniProtKB:Q5PYH7
|
881 | ||||||||||||||||
|
UniProtKB:A0A8M3B6C1
|
925 | ||||||||||||||||
|
UniProtKB:A0A8M3B3C7
|
1042 | ||||||||||||||||
|
UniProtKB:A0A8M3AWY5
|
967 | ||||||||||||||||
|
UniProtKB:A0A8M3AWY0
|
987 | ||||||||||||||||
|
UniProtKB:A0A8M3AWV0
|
1057 | ||||||||||||||||
|
UniProtKB:A0A8M3BD37
|
1030 | ||||||||||||||||
|
UniProtKB:A0A8M3B3C4
|
1063 | ||||||||||||||||
|
UniProtKB:A0A8M3B3D4
|
968 | ||||||||||||||||
|
UniProtKB:A0A8M3AWY7
|
1040 | ||||||||||||||||
|
UniProtKB:A0A8M3AWW1
|
977 | ||||||||||||||||
|
UniProtKB:A0A8M3B3C1
|
1083 | ||||||||||||||||
|
UniProtKB:A0A8M3BD36
|
1059 |
Interactions and Pathways
No data available
Plasmids