Gene

ift122

ID
ZDB-GENE-040426-2449
Name
intraflagellar transport 122 homolog (Chlamydomonas)
Symbol
ift122 Nomenclature History
Previous Names
  • zgc:77217 (1)
Type
protein_coding_gene
Location
Unmapped
Description
Involved in several processes, including animal organ development; melanosome transport; and opsin transport. Predicted to localize to ciliary basal body; intraciliary transport particle A; and non-motile cilium. Used to study retinal degeneration. Human ortholog(s) of this gene implicated in Sensenbrenner syndrome. Is expressed in several structures, including nervous system; neural plate; neural rod; pronephric duct; and pronephric mesoderm. Orthologous to human IFT122 (intraflagellar transport 122).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ift122 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cranioectodermal dysplasia 1 Alliance Cranioectodermal dysplasia 1 218330
Associated With ift122 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR039857 Intraflagellar transport protein 122/121 homolog
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Intraflagellar transport protein 122/121 homolog WD40 repeat WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q6NYH1 1187
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations