Gene
sema7a
- ID
- ZDB-GENE-030131-3633
- Name
- semaphorin 7A (JohnMiltonHagen blood group)
- Symbol
- sema7a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have chemorepellent activity; integrin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; generation of neurons; and positive regulation of macromolecule metabolic process. Predicted to localize to integral component of plasma membrane. Is expressed in Purkinje cell. Orthologous to human SEMA7A (semaphorin 7A (John Milton Hagen blood group)).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Takeuchi et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001627 | Sema domain |
Domain | IPR007110 | Immunoglobulin-like domain |
Domain | IPR016201 | PSI domain |
Family | IPR027231 | Semaphorin |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Homologous_superfamily | IPR036352 | Sema domain superfamily |
Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
Protein | Length | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Plexin repeat | PSI domain | Sema domain | Sema domain superfamily | Semaphorin | WD40/YVTN repeat-like-containing domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:E7FBE1
|
640 | |||||||||
UniProtKB:X1WHP4
|
431 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
sema7a-201
(1)
|
Havana | 3134 nt | |
mRNA |
sema7a-202
(1)
|
Havana | 1365 nt |
Interactions and Pathways
No data available
Plasmids
No data available