Gene
cenpt
- ID
- ZDB-GENE-030131-3256
- Name
- centromere protein T
- Symbol
- cenpt Nomenclature History
- Previous Names
-
- fc31h11
- fc75c05
- si:ch211-225g23.1
- wu:fc31h11 (1)
- wu:fc75c05
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and protein heterodimerization activity. Predicted to be involved in chromosome segregation; mitotic cell cycle; and protein localization to kinetochore involved in kinetochore assembly. Predicted to localize to condensed nuclear chromosome kinetochore. Used to study Seckel syndrome. Orthologous to human CENPT (centromere protein T).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from Babu et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hung et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
?Short stature and microcephaly with genital anomalies | 618702 |
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
Seckel syndrome | WT + MO3-cenpt | standard conditions | Hung et al., 2017 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | CENP-T/Histone H4, histone fold | Centromere protein T | Histone-fold |
---|---|---|---|---|
UniProtKB:A0A8M6Z3Y5
|
901 | |||
UniProtKB:E9QIT3
|
914 | |||
UniProtKB:A0A8M6YX66
|
919 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
si:ch211-225g23.1-201
(1)
|
Havana | 3125 nt | |
mRNA |
si:ch211-225g23.1-202
(1)
|
Havana | 543 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance